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The protein encoded by this gene is a member of the pexin family It is found in serum and tissues and promotes cell adhesion and spreading inhibits the membrane damaging effect of the terminal cytolytic
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Image Search Results
Journal: Scientific Reports
Article Title: Extracellular vesicle integrins act as a nexus for platelet adhesion in cerebral microvessels
doi: 10.1038/s41598-019-52127-3
Figure Lengend Snippet: RGD protein expression in extracellular vesicles (EVs) in ischemic stroke . ( a ) Triphenyltetrazolium chloride-stained brain slices of rats after tMCAO show ischemic brain areas (outlined – right panel). EVs were isolated and measured using light scattering technology in the serum of sham ( b ) and tMCAO ( c ) animals. Quantification was performed for both size ( d ) and number of EVs/ml ( e ). Representative Western immunoblots ( f ) and summary of densitometry data ( g ) show changes in expression of integrin αIIb, thrombospondin-1 (TSP-1), CD40 ligand (CD40L) and vitronectin (VTN) in EVs isolated from sham-operated or tMCAO rats. Average-fold change in peptide sequences identified as vitronectin ( h ) and thrombospondin-1 ( i ) in EVs harvested from patients with ischemic stroke and age-matched controls, as measured using LC-MS/MS. Data are mean ± SEM; *p < 0.05.
Article Snippet: VTN-MPs were incubated with
Techniques: Expressing, Staining, Isolation, Western Blot, Liquid Chromatography with Mass Spectroscopy